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They are not intended for human or animal use, bodily introduction, consumption, administration, therapeutic use, diagnostic use, cosmetic use, dietary supplement use, or any form of clinical application

It raises IGF-1 levels (which can drive cell growth), can affect blood sugar regulation, and carries risks of promoting unwanted tissue proliferation

Conditions associated with high B12 include liver disease, renal impairment, myeloproliferative disorders, and certain malignancies

Pregnenolone is produced from cholesterol, and depending upon the environmental needs, it will form into various amounts of progesterone, cortisol, aldosterone, and DHEA

The search strategy, developed according to PRISMA, and Cochrane best practices, encompassed five major databases (PubMed/MEDLINE, Cochrane Library, Google Scholar, ClinicalTrials.gov, and ProQuest) alongside manual searches of key references, grey literature, and clinical trial registries to ensure comprehensive retrieval of both published and unpublished studies