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Atherosclerosis. Nature 407: 233241

Immune peptides function as modulators, steering inflammation either up or down as necessary

This provides direction for treatment options for gliomas

It is known that autophagy is defective in dopaminergic neurons in the SN, as observed in post-mortem brains of patients and certain models of PD like 6-OHDA and rotenone-induced models, which show suppression of mTOR, a key enhancer of autophagy (Grassi et al., 2018)

Interestingly, in NRAS -mutant melanoma cells without BRAF mutations, mesenchymal-like cells were shown to survive MEKi treatment 42
