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From a wider perspective, an increased ROS burden can lead to uncontrolled cellular proliferation, culminating in DNA perturbation and an increased risk of cancer [27]

DFO and its derivatives still have limited clinical use outside of its original indication, i.e., iron poisoning

doi: 10.1016/j.fertnstert.2006.11.193 29 PazinDEAlbrechtKH

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