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Description
It also plays an essential role in the glutathione antioxidant cycle and is required to regenerate reduced glutathione
Cytoskeletal remodeling is an early manifestation of podocyte injury in DKD
(0.280.18) mm, t=2.56, P=0.016]
A structural model for GroEL-polypeptide recognition
mtUPR While GA agents have shown the capacity to modulate cellular proteotoxic quality control pathways, including those in the endoplasmic reticulum, attention to mitochondrially-specific pathways arose following observations of mismatch between elevated ROS production and decreased mitochondrial antioxidant response in rodent models (14, 122)
