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Mice lacking TRPV4 channels are less sensitive to mechanical stress (131) whereas mice with ablated TREK/TRAAK channels are hypersensitive to mechanical forces and local pH changes (136)

Wellness clinics offering 'glutathione IV drips' without individualized prescriptions are operating in a compliance gap the FDA has flagged but not systematically enforced

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HW: Writing original draft, Data curation, Methodology

[26] identified elevated plasma neurofilament light chain (NfL) levels in ME/CFS patients, which was correlated with cognitive deficit and autonomic dysfunction, thus implicating NfL as a promising biomarker for neuroaxonal damage and associated neurological dysfunction in ME/CFS