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Similarly, the common reference to DN as premalignant (or pre-melanoma) lesions suggests they are analogous to actinic keratoses or colon polyps which do evolve (albeit at very low rates) to carcinoma

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The current recommendations remain those of following a carbohydrates-rich diet with a limited fats intake and reducing, even excluding, physical activity, without, however, taking into account the long-term consequences of this approach