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High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinsons disease

10.1089/neu.2011.1858 195 ZhuH.-t.BianC.YuanJ.-c.ChuW.-h.XiangX.ChenF.et al (2014)

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Most patients tend to be diagnosed around middle age (13), but diagnosis has been made in individuals as young as three years old and as old as 77 years (2, 12)
