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Loss of muscle carnitine palmitoyltransferase 2 prevents Diet-Induced obesity and insulin resistance despite Long-Chain acylcarnitine accumulation

Zhu J-L, Cai Y-Q , Long S-L, Chen Z, Mo Z-C

Additionally, it significantly mitigated inflammation induced by oxidative damage significantly by reducing plasma MDA levels and lowering the release of pro-inflammatory cytokines (CRP, IL-1ra, and MCP-1), furthermore, attenuated TLR4-mediated hepatic inflammation by reducing plasma LPS and zonulin levels in MASLD patient [67]

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