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The resulting autoantibodies could potentially target components of the ECM or cell surface receptors on fibroblasts, influencing their behavior and contributing to the fibrotic process (122)

Rather than allowing peptide use to remain confined to nonmedical distribution channels, orthopedics should lead the development of standardized perioperative registries and prospective trials using verified formulations, with the goal of determining whether peptide-based therapies can be safely integrated into evidence-based surgical optimization

These simple steps prevent the kind of contamination that turns a good peptide into a bacterial culture medium

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