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62,63 Although the usefulness of PSQI has been validated in multiple clinical trials, it is limited by its dependence on accurate memory and should be used in conjunction with objective assessments, especially in elderly adults

Menezes, FS., Constituintes Apolares do Fruto do Aa., III Simpsio Brasileiro de Farmacognosia , Curitiba , 2001 , 2001Conference Paper, 2001 GABRIEL, Felipe Teixeira

If the pain is severe, treatment with opioids should be considered

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Clinical studies and population-based evidence Several observational and clinical studies have examined the association between circulating TMAO levels and cardiovascular outcomes in diverse populations