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GPX4 plays an important role in red cell development, as two recently published papers showed that Gpx4 -knockout mice are phenotypically characterized by ineffective erythropoiesis (Canli et al., 2016

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Huang J, Fan H, Li C, Yang K, Xiong C, Xiong S, Feng S, Chen S, Wang B, Su Y, Xu B, Yang H, Wang N, Zhu J (2024) Dysregulation of ferroptosis-related genes in granulosa cells associates with impaired oocyte quality in polycystic ovary syndrome

88, 10141019.10.1111/j.1651-2227.1999.tb00199.x 8 BerglundL.AngelinB.BlomstrandR.DrummondG.KappasA