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JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16

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Additionally, co-incubation of inflamed RAW 264.7 cells with Mn@mHSA, P-Mn@mHSA, or P-Mn/TI@mHSA resulted in an increase in CD206-positive cells, with the most pronounced effect observed in cells treated with P-Mn/TI@mHSA (Supplementary Fig

Abbreviations BDL: Bile duct ligation CAT: Catalase CCl 4 : Carbon tetrachloride CDNB: 1-Chloro-2,4-dinitrobenzene DDC: 3,5-Diethoxycarbonyl-1,4-dihydrocollidine DMN: Dimethyl nitrosamine DMSO: Dimethyl Sulfoxide FTIR: Fourier Transform Infrared Spectroscopy GPx: Glutathione peroxidase GR: Glutathione reductase GSH: Glutathione GST: Glutathione-S-Transferase H 2 O 2 : Hydrogen peroxide LC: Liver cirrhosis LDH: Lactate dehydrogenase MASH: Metabolic dysfunction-associated steatohepatitis MASLD: Metabolic dysfunction-associated steatotic liver disease MEP: Molecular electrostatic potential analysis NAD: Nicotinamide adenine dinucleotide NADH: Nicotinamide adenine dinucleotide reduced NBT: Nitro blue tetrazolium NCI: Non-covalent interactions PAGE: Polyacrylamide gel electrophoresis PDB: Protein data bank RDG: Reduced density gradient ROS: Reactive oxygen species RuCl 3 : Ruthenium Trichloride RuO 2 : Ruthenium oxide SEM: Scanning electron microscopy SOD: Superoxide dismutase TAA: Thioacetamide TEM: Transmission electron microscopy TEMED: Tetramethylenediamine XRD: X-ray diffraction References Pandey, K., Dash, D