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Fluorescence microscopy studies have documented rapid cellular accumulation, with detectable intracellular concentrations within 30 minutes of external application at physiological concentrations

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Analyses of the enzymatic activities of AST and ALT were performed according to the manufacturers instructions (Sigma-Aldrich, Milan, Italy)

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4 Ferroptosis and other forms of cell death Ferroptosis is an iron-dependent form of cellular necrosis driven by the abnormal accumulation of lipid peroxides