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It has been shown in animal studies to be important in wound healing and inflammatory responses
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Special dietary considerations include lactose restriction (present in ~ 76% of HT patients), which can lower TSH and improve levothyroxine absorption (Mikulska et al
doi: 10.1172/JCI118104
The goal of the 3R Principle is to avoid animal experiments altogether (Replacement) and to limit the number of animals (Reduction) and their suffering (Refinement) in tests to an absolute minimum
