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Adipocyte hypertrophy, inflammation and fibrosis characterize subcutaneous adipose tissue of healthy, non-obese subjects predisposed to type 2 diabetes

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During this process, astrocyte-derived type I collagen is upregulated, coinciding with the onset of neuronal death

Depending on the redox state of the free cysteine residue (Cys34), HSA exists in both reduced and oxidized forms 14,19
