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Additionally, this review delineates the commonly employed disease models (in silico, in vitro, ex vivo, and in vivo models), pharmacological research methodologies (efficacy assays, omics technologies, and target validation), and modification strategies (including drug modification and drug delivery systems) utilized in anticancer research involving natural compounds (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Toaldo I.M., Cruz F.A., Da Silva E.L., Bordignon-Luiz M.T
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