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Keywords: amino acid, botulinum neurotoxin, collagen, hyaluronic acid, intradermal injection, needle-free jet injector, poly-(lactic acid), polycaprolactone, polydeoxyribonucleotide, skin booster Introduction Aging manifests as progressive skin deterioration, weakening its structure and aesthetic appeal with dullness, dehydration, and loss of elasticity

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doi: 10.1016/j.molcel.2018.10.022 45 RonneauS.HelaineS