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Examples include ADHD stimulants like methylphenidate (Ritalin) or amphetamine salts (Adderall), which can improve focus and working memory in patients (and are sometimes misused by healthy individuals)

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Extended use isnt well-studied in humans, so most experts recommend cycling it, typically 48 weeks on, followed by a few weeks off, to support safety and effectiveness.

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However, these DATs improve some of these pharmacokinetic and pharmacodynamic problems only slightly 10 , either because they remain l-dopa based or because a large proportion of the oral treatment is usually maintained

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