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Other disorders related to vascular obstruction, particularly stroke and retinopathy leading to loss of visual acuity and even blindness, can take a devastating toll

Intervention Strategies: Anti-VEGF neutralizing antibodies (e.g., bevacizumab/B20) or anti-angiogenic tyrosine kinase inhibitors (e.g., axitinib), by blocking VEGF signaling, not only reduce pathological angiogenesis, edema, and hemorrhage but also decrease peripheral nerve density mediated by the interaction of VEGF with neuropilin (NRP), thereby alleviating pain

All controlled studies referenced below were conducted in cell culture (3T3-L1 adipocytes, primary muscle stem cells) or rodent models (diet-induced obese mice, aged C57BL/6J mice)

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Consider a dedicated mini-fridge for research materials if you use peptides regularly