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Description
A promising approach to enhancing therapeutic outcomes involves targeting mechanisms of CICD, including inducing ferroptosis by SLC7A11 inhibition, modulating mitochondrial ROS generation, or combining inhibition of autophagy with chemotherapy
In vivo , adding hydroxycitrate (250 mg/kg) and LA (10 mg/kg) to cisplatin or methotrexate was more effective against tumour development than individual chemotherapeutic drugs or the combination of lipoic acid and hydroxycitrate administered [106]
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Therefore, the effects of supplementation should always be interpreted in light of dietary consumption, geographic location, and baseline iodine status
GP1 is found in the cytoplasm of nearly all mammalian tissues, whose preferred substrate is hydrogen peroxide
