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T cells not only passively adapt to their surroundings but also actively shape the environment by producing metabolites such as lactate

Understanding these changes may help with early detection and better clinical outcomes

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[DOI] [PubMed] [Google Scholar] 17.Zhang W, Tung CH

In one illustrative, but non-limiting embodiment, the signaling domain of CD3-zeta is encoded by a nucleic acid that comprises or consists of the sequence AGAGTGAAGT TCAGCAGGAG CGC AGACGCC CCCGCGT AC A AGC AGGGCC A GAACC AGCTC T ATAACGAGC TCAATCTAGG AC G A AG AG AG GAGT AC GATG TTTTGGACAA GAGACGTGGC CGGGACCCTG AGATGGGGGG AAAGCCGAGA AGGAAGAACC CTCAGGAAGG CCTGTACAAT GAACTGCAGA AAGATAAGAT GGCGGAGGCC TACAGTGAGA TTGGGATGAA AGGCGAGCGC (SEQ ID NO:81)