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One of the dangers from lipid peroxidation besides membrane damage is the production of byproducts such as 4-hydroxy-2-nonenal (HNE)
Macrophage depletion prevented not only the rise in IL-1 (Fig
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Moreover, cancer cells carrying mutations of succinate dehydrogenase, fumarate hydrolase or isocitrate dehydrogenase accumulate -KG competitors including succinate, fumarate and 2-hydroxyglutarate, respectively 43,49,50
& Van de Kuilen, G
