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Ulcerative stomatitis and exacerbations of inflammatory bowel disease have been noted during post-marketing surveillance with ketorolac or other NSAIDs

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The SCF/c-kit mediated signalling pathway is activated by the binding of the SCF to the receptor called tyrosine-protein kinase kit (c-kit)

For instance, Treg cells isolated from patients with autoimmune diseases exhibit impaired immune suppression and reduced expression of anti-inflammatory molecules like IL-10 and CTLA-4 (74)
