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After rational design, MOFs can be endowed with intrinsic GSH-responsiveness and depletion capability

Treatment of rat cortical neurons with okadaic acid reportedly inhibits PP2A activity, resulting in an abnormal increase in mitochondrial ROS and mitochondrial fission (204)

In addition, cationic nanoparticles (CNP-siCCR2) encapsulated with siCCR2 can effectively inhibit the expression of CCR2 in monocytes and blocking the recruitment of monocytes to tumor tissues thereby changing the tumor immune microenvironment, inhibiting primary tumor growth and reducing tumor metastasis, and improving the anti-tumor effect of chemotherapy drugs (29)

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Up-regulation of glutamate in painful human supraspinatus tendon tears
