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In plants, these motifs are VNAS[R/K/Q]CG, LAFPCNQF, and WNF(S/T)KF, wherein three primary catalytic centers are presented as cysteine (Cys) or selenocysteine (Cys)-Glutamine (Gln)-Tryptophan (Trp) ( in silico and in vitro studies of protein-ligand or protein-protein interactions, could clarify the specific roles of these motifs (Ltoff et al., 1998

IL4I1 was a metabolic immune checkpoint and up-regulated in GBM [44], which could promote tumor progression in GBM [45], and IL4I1-driven AHR was a new signature in GBM as well [46]

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