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Description
The mainly vesicular intracellular localization of MRP1 in STB and pFECs was puzzling given the fact that these drug transporters are generally considered to be cell surface localized and to mediate drug resistance by lowering total intracellular drug concentrations

The pungency of Garlic: activation of TRPA1 and TRPV1 in response to allicin

Mutat Res Genet Toxicol Environ Mutagen 827:5967

282 Mechanistically, this might occur via the downregulation of TJ-related mRNA expression (e.g., occludin, CLDN1/3/4, and ZO-1)

Although some collaborations initially focused on metabolic and cardiovascular diseases, Exscientia has recently expanded into immunotherapy and inflammatory targets
