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This makes it a promising focus area in research related to chronic inflammatory conditions and autoimmune disorders

Front Immunol (2018) 9:1028

This creates a devastating feedback loop: the lack of glutathione allows oxidative stress to run rampant, which further impairs the methylation cycle, which in turn prevents the production of more glutathione

J Neuroendocrinol (2020) 32(11):e12888

doi:10.1016/j.jad.2012.05.022 Gibson SA, Korade , Shelton RC (2012) Oxidative stress and glutathione response in tissue cultures from persons with major depression
