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A disorder of the pituitary gland or hypothalamus that results in insufficient HGH production

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For example, the successful approval of trastuzumab for Human Epidermal growth factor Receptor 2 (HER2)-amplified metastatic BC and imatinib for BCR-ABL fusion-positive chronic myeloid leukemia marks the formal entry of cancer treatment into a new era of precision medicine (Druker et al., 2001

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In cervical cancer, tanshinone IIA stimulates the expression of miR-145, GSDMD and IL-1 to cause HeLa cell pyroptosis, but how miR-145 modulates pyroptosis-related gene expression needs to be clarified (Tong et al., 2020)