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Researchers should follow appropriate laboratory safety protocols and applicable regulations

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This oxidative damage severely impairs the mitochondria's ability to produce adenosine triphosphate (ATP), the currency of cellular energy

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How much this role vs non-transmission-related functions of Agm mediate protection in age-related dementias is less clear, but a supporting role for Agm/Glu co-transmission is consistent with Agm protection against excitotoxicity in AD models (Zhu et al., 2003)