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In this context, a newly published systematic review including seven clinical trials showed that the application of vitamin B12 supplementation for metformin-treated T2DM patients will be valuable in preventing or treating vitamin B12 deficiency and neuropathy and should be considered during the T2DM management plan[32]

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This product is strictly for laboratory research use only and must not be used for human or veterinary applications

doi: 10.1002/dta.1715

Labs must recognize that while the preservative reduces contamination risk, it does not eliminate it entirely