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Pre-incubation of cells with BSO, the inhibitor of 7-glutamylcysteine synthetase, responsible for the first step in intracellular glutathione synthesis did not change the effect of reduced glutathione on cell volume suggesting a mechanism limited to the interaction of extracellular reduced glutathione on cell membrane

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Apart from these differences, both groups of patients had similar clinical characteristics and response to standard medications used in the treatment of CVS

Notice how the numbers stay clean and manageable at this concentration
