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64 Positive effects of B12, 2500 g daily sublingually for 90 days (form not reported), have also been seen in musculoskeletal pain as a side-effect of aromatase inhibitors in patients with breast cancer, with a 34% reduction of pain

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In normal physiology it participates in hepatic fat processing and methylation reactions, and it contributes to the livers handling of triglycerides and cholesterol