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Doses greatly exceeding the nutritional requirements (for example, hundreds of milligrams daily) have not been studied in randomized trials for safety, so one should avoid mega doses in pregnancy unless treating a specific condition (such as pyridoxine-responsive seizures) under careful supervision

All documented evaluations are confined to investigational, analytical, and preclinical research models, with no application beyond laboratory-based examination

The peptide altered 127 genes in these cells, upregulating repair genes while downregulating inflammatory pathways responsible for tissue destruction

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