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Clin Nutr 38(2):485521

Key challenges include antigenic variability among tumors, limited infiltration of immune cells into the CNS, and the presence of immunosuppressive factors such as Tregs and MDSCs
Inhibition of Sphk1 in both in vivo and in vitro ICH models attenuates secondary brain injury and neuronal death, reinforcing the role of Sphk1 in ferroptosis-driven ICH pathology

doi: 10.1080/10641960802563568

Lenton KJ, et al
