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Furthermore, as activated immune cells, melanophages may communicate and stimulate dermal T lymphocytes and secrete proinflammatory cytokines, potentially sustaining the chronic status of the hyperpigmented lesion [157, 158]

Mechanism of the circadian clock in physiology

35 , e00276 (2015)

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Most signals, hormones and transcription factors affecting osteoclast proliferation, differentiation and function are co-regulated by RANKL and its downstream receptors OPG and RANK [103]
