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Further validations in terms of specificity, sensitivity, and reproducibility in larger populations (including children as well) will be required for these new markers before applications in routine clinical practice
Adoptive transfer of these arginine-conditioned CD8 + T cells inhibited tumor growth to a greater extent than the transfer of unconditioned CD8 + T cells [255]
Careful design and modification of NADs can mitigate immunogenicity, but this requires extensive testing
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