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Genetic polymorphisms are likely to be of greatest clinical significance when the polymorphic protein is in the main pathway affecting bioavailability and/or elimination and when the drug has a narrow therapeutic index ( Ch
Jin J, Qiu S, Wang P, Liang X, Huang F, Wu H, Zhang B, Zhang W, Tian X, Xu R, et al
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They consisted of 7 healthy right-handed elderly volunteers (59-80 years and 6 females), recruited from a community cultural center for elderly citizens
