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This process is crucial for the production of ATP, especially during periods of increased energy demand such as exercise or fasting

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( c-e ) Immunoblot of the indicated proteins in cells treated with the IDH1 inhibitor ( c ), cultured under glutamine starvation (GS) ( d ), or supplemented with succinate ( e ) and supplemented with KG, propionylcarnitine (Prop-Carn), or butyrylcarnitine (But-Carn)