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These results argue against the possibility that SMN deficiency leads to GABA deficiency by altering the balance of cortical cell populations, suggesting the direct involvement of neuronal cell-specific mechanisms

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10.1523/JNEUROSCI.0132-07.2007 76 Maciejewski-LenoirD.RichmanJ

At 24 months 28% of subjects treated with ALCAR 1.5 g/day died, as compared to 55% among their propensity score matched not treated subjects (OR 0.33, 95% CI 0.442.29)
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Nakano Y, Moriuchi M, Fukushima Y, Hayashi K, Suico MA, Kai H, Koutaki G, Shuto T
