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Urban and rural differences that contribute to the epidemiologic and nutrition transitions, such as urbanization, lifestyle, and possible health care access, may be underlying factors that explain these relationships in India

Imdad A, Pandit NG, Zaman M, et al

An additional, 11 non-herniated human discs were used to examine causality: half of each specimen was cultured in a manner that allowed free unconstrained swelling (similar to a herniated disc in vivo), while the other half was cultured within a perspex ring that allowed constrained swelling