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Int J Mol Sci (2012) 13(9):1110229

It is important to note that lysine supplementation may not be essential for healthy children and adolescents who obtain sufficient amounts of lysine through their diet

CrossRef Diabetes and Metabolism Journal in 2020: Good to Great In-Kyung Jeong Diabetes & Metabolism Journal.2020
doi:10.1017/S0007114511006544

Some newer supplements use delivery systems like liposomal or dihydroberberine, which may help the body absorb the compound more efficiently