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Much research is also being done with these two peptides in the setting of traumatic brain injury, stroke, and neurodegenerative diseases like ALS and Alzheimers.

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Physicians may opt to treat these patients and monitor for improvement of metabolic markers, particularly in populations at high risk of clinical vitamin B 12 deficiency, or observe these patients and periodically reassess their levels of vitamin B 12 , homocysteine, and/or methylmalonic acid

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Importantly, suspected neurological involvement from B12 deficiency warrants urgent same-day initiation of parenteral B12treatment should not be delayed while awaiting test results