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L.PatchA.-M.GingrasM.-C.et al (2016)

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Upon secretion, procollagen undergoes three steps of transformation in the extracellular space, i.e., (1) enzymatic removal of the free endings by procollagen peptidase to give rise to tropocollagen, (2) cross-linking of tropocollagen molecules to form collagen fibrils by lysyl oxidase, and (3) side-by-side cross-linking of collagen fibrils to form collagen fibers [54]

In a mouse model with MKN-45P carcinoma, the combination of 41 &Me@NP (20 g, 41 ) and irradiation with 808 nm (1 W cm 2 , 5 min) led to an approximately threefold increase in oxygen-saturated hemoglobin protein, and the protein level of unsaturated hemoglobin was decrease to one-third

This has positioned it as a subject of interest in neurobiological research, particularly in studies examining neuroprotective mechanisms and central nervous system signalling
