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The biotransformed xenobiotics that result may also have enhanced potential to induce pathology via direct interaction with cellular constituents due to their electrophilic nature

In the CNS, GSH is synthesized primarily by astrocytes and transported to neurons, where it provides oxidative resistance (Dringen and Arend, 2025)

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g , Representative flow cytometry histograms of surface markers expression in BMNs from WT (blue) and XKR8 KO (red) mice

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Di Gioia M., Zanoni I