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Calkins MJ, Manczak M, Mao P, Shirendeb U, Reddy PH (2011) Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimers disease

The safety and effects of this treatment have not been sufficiently studied in these groups

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Moreover, the SF12 scores showed a statistically significant difference in both PCS and MCS components, with an early improvement in PCS (detectable after 3 months), that may be particularly useful in treating FMS-related fatigue and physical exhaustion

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