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Another study with Akp3/ mice have shown that the IAP activity in the proximal intestine and 25-hydroxyvitamin D3-24-hydroxylase mRNA levels were decreased, while 1,25 dihydroxy vitamin D3 (1,25(OH)2D3) levels were increased compared with Akp3+/+ mice [75]
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World J Surg 41: 22832289
Physiologically, and similar to apoptosis of nucleated cells, eryptosis occurs to ultimately eliminate damaged senescent, and damaged or dysfunctional mature erythrocytes from the circulation [204]
