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Ellegaard PK, Licht RW, Nielsen RE, Dean OM, Berk M, Poulsen HE, et al

Polystyrene MPs exposure in male mice increased testicular oxidative stress and induced the activation of c-Jun NH2-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) pathways, which resulted in decreased sperm number and motility, as well as suppressed metabolism-related enzymes lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity [56]