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JPH-203, a LAT1-specific inhibitor designed based on LAT1 ligands, has a strong affinity and does not show obvious toxicity in preclinical studies

Blood glucose levels were measured at 15 min (immediately after the administration of purified water or Ltheanine), 0 min (immediately after glucose administration), and at 15, 30, 60, and 120 min postglucose administration

As a signal peptide , it sends messages to skin cells to ramp up repair and renewal

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This metabolic transformation also results in reduced affinity of the compound for its cellular target
