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This vascular recovery potential [6,30,31,32,33,34] bypassing key, the activation of the collaterals depending on the given injury [6,30,31,32,33,34], has been supported by its special interaction with essential systems in cytoprotection, the prostaglandin system (counteraction of all adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs)) [40], and then a nitric oxide (NO) system [41,42,43,44] as a whole

Histidine-tagged recombinant products were purified by affinity chromatography (Supplementary Fig

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