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Despite lower ATP production than OXPHOS does, this seemingly paradoxical metabolic phenotype provides advantages for rapidly proliferating malignant cells

Another study found that during relapse, RRMS patients exhibited increased extracellular acidification rate (ECAR) and oxygen consumption rate (OCR), which were not observed during the remission when compared to the healthy controls

[DOI] [Google Scholar] 165.Bosch G., Hagen-Plantinga E.A., Hendriks W.H

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Our data demonstrate that protein oxidation might be a major mechanism of cell death following DMF because DMF and FG4592/hypoxia cotreatment is abrogated by protective persulfidation by H 2 S